Exact Likelihood Calculation under the Infinite Sites Model
نویسندگان
چکیده
منابع مشابه
Exact Likelihood Calculation under the Infinite Sites Model
A key parameter in population genetics is the scaled mutation rate θ = 4Nμ, where N is the effective haploid population size and μ is the mutation rate per haplotype per generation. While exact likelihood inference is notoriously difficult in population genetics, we propose a novel approach to compute a first order accurate likelihood of θ that is based on dynamic programming under the infinite...
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ژورنال
عنوان ژورنال: Computation
سال: 2015
ISSN: 2079-3197
DOI: 10.3390/computation3040701